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25I-NBF

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Description

25I-NBF

25I-NBF

25I-NBF is an N-benzyl derivative of the phenethylamine hallucinogen 2C-I which acts as a highly potent partial agonist for the 5-HT2A receptor.

25I-NBF acts as a partial agonist of human 5-HT2A receptors demonstrating a Ki value of 0.26 nM and an EC50 value of 1.6 nM.

1 A radiolabelled form of 25I-NBF has been used for mapping the distribution of 5-HT2A receptors in the brain, using positron emission tomography.

2 This product is intended for forensic and research applications.

Technical Information
Formal Name
N-(2-fluorobenzyl)-2-(4-iodo-2,5-dimethoxyphenyl)ethanamine, monohydrochloride
CAS Number
1539266-13-1
Synonyms
2C-I-NBF
Molecular Formula
C17H19FINO2 • HCl
Formula Weight
451.7
Purity
≥98%
Formulation
A crystalline solid
λmax
234, 300 nm
SMILES
IC1=CC(OC)=C(CCNCC2=C(F)C=CC=C2)C=C1OC.Cl
InChI Code
InChI=1S/C17H19FINO2.ClH/c1-21-16-10-15(19)17(22-2)9-12(16)7-8-20-11-13-5-3-4-6-14(13)18;/h3-6,9-10,20H,7-8,11H2,1-2H3;1H
InChI Key
GHAILJKILCIMFT-UHFFFAOYSA-N

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25I-NBF (hydrochloride).

25I-NBF (hydrochloride).

25I-NBF (hydrochloride).

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